[HTML][HTML] Transcription factor LSF (TFCP2) inhibits melanoma growth

…, M Kumasaka, N Ohgami, A Tanaka, T Tsuzuki… - Oncotarget, 2016 - ncbi.nlm.nih.gov
… We then showed that increased LSF expression levels suppressed anchorage-dependent …
DNA-binding activity of LSF has been reported to be controlled via phosphorylation of LSF at …

BDNF signaling in epilepsy: TRKB-induced JAK/STAT pathway and phosphorylation of LSF in neurons

KE Hokenson - 2016 - open.bu.edu
Factor (LSF), a ubiquitous transcription factor that regulates … I show that BDNF through the
mitogen-activated protein … (Erk) rapidly enhances DNA-binding of LSF in primary human T

Transcription factor LSF: interactions with protein partners leading to epigenetic regulation and microtubule modifications

HG Chin - 2017 - search.proquest.com
rapidly phosphorylated by Cdk2/cyclin C on Ser-309 and by ERK on Ser-291 upon mitogenic
stimulation of multiple cell … inhibitors of LSF DNA-binding and transcriptional activation. …

Forging a functional cure for HIV: transcription regulators and inhibitors

S Mediouni, S Lyu, SM Schader, ST Valente - Viruses, 2022 - mdpi.com
… or either host transcriptional factors and chromatin regulators, … confirmed in primary cells
and resting CD4 + T cells from an … -κB in the nucleus increases its DNA-binding affinity. Several …

TFCP2 as a therapeutic nexus: unveiling molecular signatures in cancer

N Kaushik, A Jaiswal, P Bhartiya, EH Choi… - Cancer and Metastasis …, 2024 - Springer
… unusual DNA-binding activity, these transcription factors are … T lymphocytes, inducers of
cell growth can increase CP2's … The mitogenic stimulus binds TFCP2 to the essential promoter …

Coupled feedback regulation of nuclear factor of activated T-cells (NFAT) modulates activation-induced cell death of T cells

SY Shin, MW Kim, KH Cho, LK Nguyen - Scientific Reports, 2019 - nature.com
… that amplified activation of the transcriptional factor NFAT in … function known as the logarithmic
sensitivity function (LSF). … affect the levels of mitogen-activated protein kinase signaling …

HIV Expression in Infected T Cell Clones

JW Rausch, S Parvez, S Pathak, AA Capoferri… - Viruses, 2024 - mdpi.com
… upon host cell and viral transcription factors binding to an array … II transcription complexes,
CDK9-mediated phosphorylation … by DNA sequence, DNA binding proteins, and the activity of …

[PDF][PDF] critical role of the transcription factor Miz-1 in T cell activation and maturation

AS Mägdefrau - 2023 - db-thueringen.de
… These cells show a fast and efficient response to the … the linker for activation of T cells (LAT)
through phosphorylation, … of which are important for its DNA binding capacity. An important …

Transcription: insights from the HIV-1 promoter

E Ne, RJ Palstra, T Mahmoudi - International review of cell and molecular …, 2018 - Elsevier
… the majority of cellular transcription factor consensus binding sites … Most cell types, including
T cells, tightly control NF-κB activity by … Upon T cell activation by mitogens, cytokines, oxygen …

A cellular perspective of adipogenesis transcriptional regulation

W Kuri‐Harcuch, C Velez‐delValle… - Journal of cellular …, 2019 - Wiley Online Library
mitogenic effects. Adipose differentiation of the 3T3-F442A … examined the activity of the
transcription factors accepted as … bHLH protein to enhance DNA binding. It seemed logical to …